Thalassemia minor
Thalassemia Minor
Thalassemia Latest NEWS
What Are Thalassemias?
Thalassemias (thal-a-SE-me-ahs) are inherited blood disorders. "Inherited" means they're passed on from parents to children through genes.

Thalassemias cause the body to make fewer healthy red blood cells and less hemoglobin (HEE-muh-glow-bin) than normal. Hemoglobin is an iron-rich protein in red blood cells. It carries oxygen to all parts of the body. It also carries carbon dioxide (a waste gas) from the body to the lungs, where it's exhaled.

People who have thalassemias can have mild or severe anemia (uh-NEE-me-uh). This condition is caused by a lower than normal number of red blood cells or not enough hemoglobin in the red blood cells.

Normal hemoglobin, also called hemoglobin A, has four protein chains—two alpha globin and two beta globin. The two major types of thalassemia, alpha and beta, are named after defects in these protein chains.

Four genes are needed to make enough alpha globin protein chains. Alpha thalassemia trait occurs when one or two of the four genes are missing. If more than two genes are missing, the result is moderate to severe anemia.

The most severe form of alpha thalassemia is known as alpha thalassemia major or hydrops fetalis. Babies with this disorder usually die before or shortly after birth.

Two genes (one from each parent) are needed to make enough beta globin protein chains. Beta thalassemia occurs when one or both genes are altered.

The severity of beta thalassemia depends on how badly one or both genes are affected. If both genes are affected, the result is moderate to severe anemia. The severe form of beta thalassemia also is known as thalassemia major or Cooley's anemia.

Thalassemias affect both males and females. They occur most often among people of Italian, Greek, Middle Eastern, Asian, and African descent. Severe forms usually are diagnosed in early childhood and are lifelong conditions.

Doctors diagnose thalassemias using blood tests. The disorders are treated with blood transfusions, medicines, and other procedures.

Treatments for thalassemias have improved greatly in the past few years. People who have moderate and severe thalassemias are now living longer and have better quality of life than before.

However, complications from thalassemias and their treatments are frequent. People who have moderate or severe thalassemias must closely follow their treatment plans. They need to take care of themselves to remain as healthy as possible.

Thalassemia (British spelling, "thalassaemia") is an inherited autosomal recessive blood disease. In thalassemia, the genetic defect results in reduced rate of synthesis of one of the globin chains that make up hemoglobin. Reduced synthesis of one of the globin chains causes the formation of abnormal hemoglobin molecules, and this in turn causes the anemia which is the characteristic presenting symptom of the thalassemias.

Thalassemia is a quantitative problem of too few globins synthesized, whereas sickle-cell disease (a hemoglobinopathy) is a qualitative problem of synthesis of a non-functioning globin. Thalassemias usually result in under production of normal globin proteins, often through mutations in regulatory genes. Hemoglobinopathies imply structural abnormalities in the globin proteins themselves . The two conditions may overlap, however, since some conditions which cause abnormalities in globin proteins (hemoglobinopathy) also affect their production (thalassemia). Thus, some thalassemias are hemoglobinopathies, but most are not. Either or both of these conditions may cause anemia.

The disease is particularly prevalent among Mediterranean peoples, and this geographical association was responsible for its naming: Thalassa is Greek for the sea, Haema is Greek for blood.

Thalassemia Minor
Thalassemia Latest NEWS
Thalassemia Latest NEWS

  • Pre-marital tests are necessary
  • Red Cross secy offers his blood and toil for thalassemia
  • Towards a world free of Thalassemia
  • 10,000 thalassemia patients in Madhya Pradesh
  • Thalassemics face discrimination at work
  • or Mr.Rajesh Chopra is  not responsible for any wrong information under liveindia's sites,
    For confirmation of any information it is recommended that you Reconfirm it from your end.
    Privacy Policy for LiveIndia.Com
    The Taj Mahal with Gallery
    A Tribute to Beauty
    The Taj Mahal with Gallery
    Khajuraho with Gallery
    Temples of Love
    Khajuraho with Gallery
    Old Delhi and New Delhi
    Old Delhi and New Delhi
    with all Informations
    Dedicated site of Goa
    with all informations
    Virtual Tour of Rajasthan
    with Gallery
    Kerala Tour with Gallery
    Maa Ganges
    Maa Ganges
    Travel to India
    Amarnath  Shiva
    Amarnath  Shiva
    Complete Yatra (Virtual Tour)
    Live India
    Multi Dimensional 
    Entertainment magazine
    from INDIA
    World's Most Beautiful Cities
    click for Other Tourist Place